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Rare case of woman who survived 12 tumors before age 36 could help science

The Spaniard suffered 12 tumors, five of them malignant, at the age of 36 years. the first cancer was discovered when she was two years old, and the last at 28. Doctors and scientists cannot explain how she is still alive. now this The rare case could help improve early diagnosis and develop new cancer treatments worldwide.

In accordance with a country, the explanation for the appearance of so many tumors in a woman’s body can be explained by a new mutation in Human Beings that increases the appearance of cancer cells. The results of the study, published this Wednesday in the journal Science Advances, show that this woman inherited a mutated copy of the MAD1L1 gene from each of her parents.

“It was very difficult to understand how this woman managed to survive with this mutation. Something else must have helped her escape,” explains Marcos Malumbres, head of cells and cancer at CNIO. El Pais. The researchers explain that the Spaniard’s immune system reacted to tumors with generalized and continuous inflammation, that is, the defenses were always on the alert.

Although the genetic mutation doomed her to suffer from cancer much more often than other people, the immune system was extremely stimulated, which made it easier to identify and destroy tumor cells, CNIO biochemist Carolina Villarroya explains to the Spanish newspaper.

Those responsible for the study believe that this patient’s extraordinary case will help improve cancer diagnosis and develop new treatments.

Author: morning Post
Source: CM Jornal

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